Prof. Dr. Jianguo “Jack” Liu is a world leader in systems integration and sustainability (e.g., integrating ecology with social sciences, policy, and technologies for understanding and promoting global sustainability). He holds the Rachel Carson Chair in Sustainability, and is University Distinguished Professor and founding director of Center for Systems Integration and Sustainability at Michigan State University (USA). He has translated many research findings to effective policy and management for global sustainability, especially in China. Furthermore, he has amplified the impacts through helping numerous others. Liu’s pioneering research has opened up new frontiers in sustainability and greatly advanced the fundamental understanding of global challenges. He coined the integrated concept of telecoupling (socioeconomic-environmental interactions over distances), and has been leading the development and applications of the award-winning telecoupling framework. This framework helps disentangle the complexity of globalization and systematically expand sustainability science from focus on specific places separately to human-nature interactions across distant places. It provides a powerful tool to uncover hidden impacts of human activities within specific places on sustainability elsewhere. Many of his research findings have been translated into effective policies and management interventions, which have helped the recovery of a global wildlife icon (giant pandas), improved management of protected areas, and revolution of China’s environmental protection.